IndraLab

Statements

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"However, ECM-CAM interactions are also involved in a range of pathophysiological disorders, including cancer ( xref , xref – xref )."
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"Most modules included other key families of genes, such as those encoding ECM and cell adhesion molecules (CAMs); ECM–CAM interactions have been shown to markedly enhance metastatic processes."
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"Multiple myeloma (MM) provides an interesting model for studying the role of CAM-ECM interactions in the dissemination of malignant cells."
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"The results suggest that RGD-ELP promotes pseudoislet formation via up-regulation of the CAM and ECM components."
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"However, double-mutant mice lacking both gliomedin and Caspr have dramatically impaired node formation [ xref ], suggesting that paranodal junctions and ECM-CAM interactions at nodes are overlapping mechanisms to facilitate Nav channel clustering."
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