IndraLab

Statements

Methyltransferase-like binds EIF3H. 3 / 3
| 3
sparser
"Exosomal circLPAR1 and methyltransferase-like 3 (METTL3) competitively bind RBP eIF3h, effectively reducing the translation of brominated protein 4 (BRD4) and subsequently inhibiting the proliferation, invasion, and migration of colorectal cancer cells ( xref )."
37168995
sparser
"They demonstrated that circLPAR1 encapsulated in exosomes could be internalized by colorectal cancer cells, and further suppressed tumour growth by directly bound with eukaryotic translation initiation factor 3 subunit h (eIF3h), suppressing the methyltransferase-like 3 (METTL3)-eIF3h interaction and decreasing the translation of oncogene bromodomain containing 4 [ xref ]."
38711144
sparser
"Mechanistically, circLPAR1 diminishes expression of the oncogene bromodomain-containing protein 4 ( BRD4 ) by sponging eukaryotic translation initiation factor 3 subunit h (eIF3h) and preventing the interaction between methyltransferase-like 3 (METTL3) and eIF3h [ xref ]."
38741166