IndraLab

Statements


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"Isomorellin and doxorubicin and forbesione and doxorubicin treatments suppress NF-kB and p65 activation in CCA cell lines."

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"Similar to ARF, we found that UV-C, daunorubicin, and doxorubicin repressed the RelA transactivation domain when present as a Gal4 fusion protein."

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"Thus, STAT3 activation inhibits doxorubicin mediated p65 nuclear localization, which is contrary to data obtained in untreated cancer cells indicating that STAT3 promotes p65 nuclear retention XREF_BIBR."