IndraLab

Statements

LBT binds USP32. 3 / 3
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"CETSA was further performed to validate the interaction between LBT and USP32."
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"As expected, the heat challenge quickly led to USP32 denaturation and precipitation, while LBT markedly increased the thermal stability of the USP32 protein at temperatures ranging from 42 °C to 54 °C (Figure 3F), confirming the direct binding of LBT to USP32."
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"Firstly, molecular docking and molecular dynamic simulations were conducted to estimate the interaction between LBT and USP32."
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