IndraLab

Statements

ATXN3 decreases the amount of EFNA3. 3 / 3
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"These results indicate that ATXN3 represses Efna3 transcription by acting, either directly or indirectly, on the promoter region."
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"Both normal and expanded ATXN3 significantly repressed Efna3 transcription by approximately 20% but had no effect on expression of the control pGL3 luciferase vector (XREF_FIG)."
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"To identify which histone acetylases and regulators are likely involved in establishing the histone acetylation and enhanced gene expression of Efna3 induced by the loss of ATXN3, we measured their nuclear protein levels in both Atxn3-KO and WT cells."
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