IndraLab

Statements

Silibinin inhibits RELA. 3 / 4
| 3
reach
"Western immunoblot analysis further showed that silymarin reduced p65 in the nucleus (XREF_FIG)."
25954125
reach
"Results indicated that compared to their respective controls, the immunoreactivity score of total p65 decreased by 28% in silibinin fed LoVo xenografts (P < 0.05), whereas the decrease was 75% (P < 0.001) in case of SW480 (XREF_FIG)."
22086675
reach
"In vivo studies conducted in mouse models indicate that topical application of silibinin inhibits UVB induced expression levels of ERK1/2 and p38 proteins of MAPK family, and subsequently inhibited the activation of NF-kappaB and p65 through inhibition of degradation of IkappaBalpha and activation of IKKalpha."
20372777