IndraLab

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H2AB activates USP39. 2 / 2
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"Fluorescence images of mixed H2AB-RFP and Sad1 -GFP proteins showed that H2AB substantially augmented the phase separation of Sad1 -GFP (Fig. 6k–m)."
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"Moreover, it is worth noting that the 147-bp nucleosome core particle (NCP) was not able to promote the phase separation of Sad1 (Supplementary Fig. 12b), suggesting that H2AB-dependent augmentation of Sad1 phase separation relies on its specific interaction with the free H2A-H2B."
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