IndraLab

Statements


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"Thus, the CSN controls the Wnt and beta-catenin signalling by assisting the assembly of beta-catenin-degrading supercomplexes by deneddylation and, simultaneously, by stabilising APC via CSN associated USP15."

reach
"CSN controls Wnt and beta-catenin signaling by assisting with the assembly of beta-catenin-degrading supercomplexes by deneddylation and, simultaneously, by stabilizing APC via CSN associated USP15."

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"A model is provided that proposes a role of CSN mediated deneddylation in the formation of the beta-catenin-degrading supercomplex and the protection of complex bound APC via CSN associated USP15."