IndraLab

Statements

USP4 inhibits MAP3K7. 4 / 10
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"We also found that overexpression of USP4 inhibited TAK1 but not IKKβ-induced NF-κB activation in a reporter assay ( xref )."
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"USP4 inhibits TAK1 and TAB1 co-overexpression-mediated NF-kappaB activation."
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"XREF_BIBR showed that USP4 could block Dox induced activation of NF-kappaB at the early stage of the treatment by preventing TAK1 from conjugating K63 linked polyubiquitin chains."
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"We also found that overexpression of USP4 inhibited TAK1 but not IKKβ-induced NF-κB activation in a reporter assay ( xref )."
21331078