IndraLab

Statements



reach
"USP3 upregulation attenuated IL-1β-mediated apoptosis of chondrocytes and inactivation of NF-κB pathway (107)."

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"Our results show that overexpression of USP3 could inhibits IL-1β-induced apoptosis, indicating that USP3 may be a negative regulator of OA development."

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"Despite it has been demonstrated that ubiquitin-specific protease 3 (USP3) inhibits chondrocyte apoptosis induced by interleukin (IL)-1β, the role of USP3/SIRT3/FOXO3 in the senescence of chondrocytes in OA is unclear."