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Deubiquitinase activates USP8. 2 / 2

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"Moreover, we found that overexpression of Ubpy/USP8, an autophagy-related DUB, could not suppress the Atg1-induced eye defects (Fig. 4H, H’), suggesting that the interaction between Leon and Atg1 is DUB specific."

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"HBX 90,397, another DUB-specific inhibitor, blocks USP8 activity."

| PMC

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IndraLab

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Deubiquitinase activates USP8. 2 / 2

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