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Mutated USP46 increases the amount of ITGB1. 1 / 1

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"In contrast, re-expression of the catalytically inactive USP12 or USP46 mutants, in which the catalytic site cysteine was substituted for serine (Li et al, 2016; Yin et al, 2015), were unable to restore the Itgb1 levels indicating that USP12/46 require the DUB activity to maintain the 125 kDa mature Itgb1 levels (Figs."

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IndraLab

Statements

Mutated USP46 increases the amount of ITGB1. 1 / 1

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