IndraLab

Statements


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"Several polymorphisms have been identified as being responsible for the impaired activity of the CYLD gene, which finally leads to the tumorigenesis [23, 24]."

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"CYLD modulated PCa tumorigenesis and ferroptosis in vivo."

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"CYLD has also been shown to deubiquitinate (and inactivate) the coactivator BCL‐3 (117), which switches the transcriptional properties of NF‐κB from repressive to activating, and is known to strongly promote cell proliferation and oncogenesis (118, 119)."