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(20S)-ginsenoside Rg3 activates KCNH2. 3 / 3

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"RPR260243 and ginsenoside Rg3 slow the rate of hERG1 channel deactivation."

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"It has been reported that ginsenoside Rg3 (Gin Rg3) can increase the current amplitude of hERG and slow the deactivation of tail current."

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"However, a study on the QT prolongation induced by the anti-thyroid cancer drug vandetanib showed that ginsenoside Rg3 combined with vandetanib could increase the inactivating current of hERG Kchannel, thereby reversing the QT prolongation [116]."

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(20S)-ginsenoside Rg3 activates KCNH2. 3 / 3

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