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Catalytically active USP7 increases the amount of BMI1. 1 / 1

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"Regulation of the stability of the PRC1 complex also appears to be another facet, as the de-ubiquitination of the PRC1 components BMI1 and MEL18 by the ubiquitin-specific proteases 7 and 11 has been shown to increase their abundance (Maertens et al., 2010), whereas the loss of these ubiquitin-specific proteases promotes INK4A transcriptional activation."

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IndraLab

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Catalytically active USP7 increases the amount of BMI1. 1 / 1

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