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USP19 activates epithelial to mesenchymal transition. 3 / 3

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"Moreover, USP19-ER inhibits TGF-beta-induced epithelial-mesenchymal transition (EMT), whereas USP19-CY enhances EMT, as well as the migration and extravasation of breast cancer cells."

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"These results suggest that USP19-CY promotes TGF-β-induced EMT, as well as basal and TGF-β-mediated cell migration and invasion."

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"In contrast, USP19-CY promotes TGF-β/SMAD-induced breast and lung cancer cell EMT, cell migration and extravasation in vitro and in vivo."

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USP19 activates epithelial to mesenchymal transition. 3 / 3

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