IndraLab

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BAP1 activates Histone. 2 / 2

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"The BAP1 nuclear deubiquitinase is known to target histones (together with ASXL1 as a Polycomb repressor subunit) and the HCF1 transcriptional co-factor, and we show that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes."

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reach

"BAP1 is a deubiquitinase targeting histones and the host cell factor-1 transcriptional co-factor, and plays a role in transcriptional regulation, chromatin modulation, cell cycle regulation, and DNA repair."

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IndraLab

Statements

BAP1 activates Histone. 2 / 2

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