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UCHL1 activates ACTN4. 1 / 1

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"Our data suggest that UCHL1 upregulation in ACTN4 associated FSGS fuels the proteasome and that UCHL1 deletion may impair proteolysis and thereby preserve K256E and wt-alpha-actinin -4 heterodimers, maintaining podocyte cytoskeletal integrity and protecting the glomerular filtration barrier."

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IndraLab

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UCHL1 activates ACTN4. 1 / 1

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