IndraLab

Statements

ATXN3 deubiquitinates BECN1. 4 / 5
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"ATXN3 deubiquitinates BECN1, which prevents it from being degraded."
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"Ataxin-3 deubiquitinates beclin-1 that then escapes proteasomal destruction and triggers starvation-induced autophagy."
| PMC
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"ATXN3 also interacts with VCP (/p97), an ATPase complex, that thereby facilitates the deubiquitination of BECN1 by ATXN3 [52]."
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"ATXN3 is also known as a regulator of autophagy by deubiquitinating Beclin 1 (Ashkenazi et al., 2017)."
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