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Acetic acid activates SCN8A. 1 / 1
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"Direct, naloxone-reversible analgesic effects of SCH 34826 were demonstrated in the mouse low temperature hot-plate test (MED = 30 mg/kg p.o.), the mouse acetic acid induced writhing test (MED = 30 mg/kg p.o.), the rat stress induced analgesia test (MED = 10 mg/kg p.o.) and the modified rat yeast-paw test (MED = 100 mg/kg p.o.)."