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Bilobalide inhibits RELA. 2 / 2
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"In an LPS-induced cell model, the G. biloba extract bilobalide reduced p65 accumulation in the nuclei and re-freed it to the extracellular compartment, suggesting that bilobalide inhibited M1 polarization by improving NF-κB pathway activation [60]."
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"Furthermore, ginkgolide and bilobalide also downregulated p-TAK1, p-IkBalpha, and p-IKKbeta and inhibited the OGD/R induced transfer of NF-kappaB p65 from cytoplasm to nucleus in BV2 microglia cells."
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