IndraLab

Statements



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"Vitamin D and its metabolites could inhibit T-cell proliferation and suppress production of interleukin 1, interleukin 2, tumor necrosis factor alpha and interferon-beta [16,17,25,26]."

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"Thus, vitamin D inhibits RSV induction of NF-kappaB-driven IFN-beta and CXCL10 secretion, as also demonstrated in this study."

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"If vitamin D suppresses IFNbeta induction and, subsequently, interferon driven genes which have diverse antiviral activities, then how is the antiviral state maintained?"

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"Vitamin D augmentation of IFN responses was seen in untreated and in IFN-beta-1b-treated MS. The combination of vitamin D plus IFN-beta reduced Th1 and Th17 cytokines, and increased Th2 responses, reversing the effect of IFN-beta alone."