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USP24 bound to GSDMB activates STAT3. 2 / 2

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"Here, our results indicated that USP24 bound to GSDMB to stabilize GSDMB, and subsequently activated the STAT3 pathway in bladder cancer cells."

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"In bladder cancer, the USP24/GSDMB/STAT3 axis is reported to promote tumor proliferation and growth, where USP24 interacts and stabilizes GSDMB, which in turn binds to STAT3, increases its phosphorylation and activates STAT3 signaling (30)."

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IndraLab

Statements

USP24 bound to GSDMB activates STAT3. 2 / 2

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