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Olanzapine inhibits KCNH2. 2 / 2

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"Olanzapine inhibited hERG tail currents at -50 mV in a concentration dependent manner with an IC50 value of 8.0 muM and a Hill coefficient of 0.9."

26484507

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"Olanzapine also decreased the hERG current elicited by a 5s depolarizing pulse to +60 mV to inactivate the hERG currents, suggesting an inhibition of the activated (open and/or inactivated) states of the channels."

26484507

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IndraLab

Statements

Olanzapine inhibits KCNH2. 2 / 2

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