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USP1 inhibits DNA repair. 2 / 2

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"Mutation of aspartic acid 199 in USP1 disrupts its deubiquitinating activity and impairs DNA repair."

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"Initial evidence suggested that USP1 inhibition leads to constitutive DNA repair and protects cells from MMC induced chromosome aberrations [45]."

19264559

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP1 inhibits DNA repair. 2 / 2

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