IndraLab

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CD44 binds ADAM17. 2 / 2

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sparser

"This observation together with our findings suggests that TPA-mediated Rac activation promotes the redistribution of both pro form of ADAM17 and CD44 to the plasma membrane, leading to ADAM17 activation and clustering of the activated protease and substrate, which might be required for triggering the proteolytic processing."

15197174

➶

sparser

"Conversely, no colocalization of ADAM17 and CD44 could be detected ( Figure 7b ) indicating that there is no constitutive interaction between CD44 and ADAM17."

18971959

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IndraLab

Statements

CD44 binds ADAM17. 2 / 2

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