IndraLab

Statements

KCNH2-S636A activates clemizole. 1 / 1

| 1

reach

"The S631A, S636A, Y652A and F656V hERG mutant channels reduced the inhibitory effect of clemizole (IC 50 : 0.82, 0.89, 1.49 and 2.98 muM, respectively), suggesting that clemizole is a pore blocker of hERG channels."

27886373

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

KCNH2-S636A activates clemizole. 1 / 1

INDRA sources:

Databases

Reading