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USP2 increases the amount of MMP2. 2 / 3
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"This study also showed that USP2 upregulates MMP2 expression and induces the motility and invasiveness of TNBC cells [XREF_BIBR]; however, it remains unknown whether MMP2 is a direct substrate of USP2."

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"USP2 was found to promote MMP2 expression and its upregulation is associated with enhanced invasiveness of breast cancer cell lines [ 105 ]."