IndraLab

Statements


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"Tepoxalin also inhibits the activation of NFKB, a transcription factor which acts pn several cytokine genes."

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"Whether Tepoxalin inhibits NF-KB induc- tion by other ER stress- eliciting agents remains to be investigated."

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"Certain analogs of tepoxalin that had previously been shown to inhibit NF-KB activation were also the most potent inhibitors of PGHS1 peroxidase activity."

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"Its immunosuppressive property is distinct from cyclosporin because only tepoxalin, but not cyclosporin, suppresses NF-KB activation."