IndraLab

Statements


YY1 activates USP43. 2 / 2
| 2

sparser
"Mechanistically, USP43, which is transcriptionally activated by YY1, stabilizes FASN through deubiquitination, and FASN activates SLC7A11 expression by stabilizing HIF1α."

sparser
"Mechanistically, USP43 is transcriptionally activated by YY1 and stabilizes FASN by inhibiting its ubiquitination and degradation."