IndraLab

Statements

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"In brief, USP9X promoted the migration and invasion of PANC-1 cells probably by provoking epithelial-mesenchymal transition, and also inhibited apoptosis."
29130109
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"Inhibition of USP9X by its inhibitor WP1130 reduced the migration and invasion of NSCLC cells."
29423007
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"USP9X and TKK promote proliferation, invasion and migration in LUAD cells77.Interestingly, USP9X exerts different functions in different cancers."
34405018
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"G9 mediated inhibition of Usp9x in pancreatic cancer cells not only reduced the in vitro 3D growth and invasion but also inhibited tumor growth of human pancreatic cancer MIAPACA2 cells in vivo."
29248719
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"Pal et al. reported that overexpression of USP9X promoted the proliferation and invasion of pancreatic cancer cells [ 25 ]."
30118840
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"Thus, based on the present findings, it is proposed that USP9X downregulation promotes invasion and migration through the induction of MMP9 and mitochondrial fission, which, to the best of our knowledge, has not been reported in other types of cancer.To further elucidate how USP9X induces MMP9 and p-DRP1, several upstream signaling pathways were tested, and ERK signaling was revealed to be upregulated following the silencing of USP9X."
31002345
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"Usp9x expression increases cell survival and 3D growth, and induces invasion in human PDAC cell line PANC1."
29248719
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"As both USP9X and RNF115 have been reported to promote breast cancer cell proliferation, migration, and invasion,13, 20, 21, 23 we next determined whether the biological function of USP9X in breast cancer cells depends on RNF115."
30689267
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"The results of plate clone formation assay, CCK8 assay, cell scratch migration test, transwell assay, and flow cytometry indicated that USP9X could significantly promote the proliferation and invasion of FaDu cells, in addition to inhibiting apoptosis."
37057289
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"In addition, cell migration and invasion were promoted by USP9X overexpression."
35865393
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"However, USP9X knockdown inhibited cell migration and invasion in Z-138 and Jeko-1 (Figure 4C, D)."
35865393
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"USP9X deficiency in HGC-27 and MKN-45 cells causes decreased proliferation, cell cycle arrest, extra apoptosis, and defective migration and invasion, which could be rescued by excessive MTH1."
39075342
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"Importantly, reintroduction of RNF115 in USP9X-depleted cells partially rescued the reduced proliferation, migration, and invasion of breast cancer cells by USP9X knockdown."
30689267
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"Furthermore, USP9X inhibition also reversed the increased migration and invasion mediated by miR-132 inhibition."
29423007
eidos
"Cell migration and invasion were significantly inhibited by down-regulation of USP9X ."
36047196