IndraLab

Statements

SHMT2 binds BRCC3. 5 / 5
2 | 3
biogrid
No evidence text available
28514442
reach
"Interestingly, we revealed that BRCC36 knockdown decreased beta-catenin expression in CRC cells, suggesting that binding between SHMT2 and BRCC36 may direct BRCC36 activity towards K63-Ub chains conjugated to beta-catenin in CRC cells."
33456583
reach
"SHMT2 reportedly binds to BRCC36 and acts as an apparent competitive inhibitor for BRCC36 XREF_BIBR."
33456583
biogrid
No evidence text available
19615732
reach
"Given that SHMT2 and BRCC36 complexes work together to promote K-63 ubiquitin deubiquitination XREF_BIBR, we investigated whether BRCC36 is involved in beta-catenin deubiquitination."
33456583