IndraLab

Statements

TNFAIP3 inhibits TNFAIP3. 3 / 3
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"A20 potently inhibited growth of A20 transfectant ACC-2-A20 compared with control vector transfected groups and the ACC-2 empty control group (P < 0.05)."
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"A previous study shows that TNFAIP3 expression level is diminished in monocytes and CD4 + T cells of MS patients, suggesting TNFAIP3 plays a role in anti-inflammatory pathways, which might contribute to MS risk [46]."
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"Mutant TNFAIP3 (A20)-transfected cells showed increased TRAF6 polyubiquitination, suggesting the loss of function of TNFAIP3 (A20) deubiquitination activity in the mutant protein (Fig 6)."
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