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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

SCN8A decreases the amount of OLR1. 4 / 4

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"In our present study, MED could significantly inhibit RAW 264.7 cells transformation into foam cells and LOX-1 expression induced by ox-LDL, which indicated that the suppression of LOX-1 expression by MED contributes to its inhibitory effects on macrophage foam cell formation."

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"MED inhibits ox-LDL-induced LOX-1 expression in macrophages."

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"XREF_FIG, MED significantly inhibited the LOX-1 protein levels in a dose dependent manner."

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"XREF_FIG, MED significantly suppressed the mRNA levels of LOX-1, which indicated that MED may inhibit ox-LDL-induced LOX-1 expression at the transcriptional level."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

SCN8A decreases the amount of OLR1. 4 / 4

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