IndraLab

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USP14 inhibits 2,5-diphenylfuran. 2 / 2

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"Although PPF is usually inversely related to release probability, USP14 deficiency impairs PPF without altering basal release probability."

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"Finally, the PPF deficit caused by loss of USP14 can be rescued by pharmacological inhibition of proteasome activity, suggesting that inappropriate protein degradation underlies the PPF impairment."

24218545

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IndraLab

Statements

USP14 inhibits 2,5-diphenylfuran. 2 / 2

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