IndraLab

Statements

USP7 inhibits localization. 3 / 3
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"Unlike normal HeLa cells, showing co-localization of HAUSP and ANXA1 in the nucleus by forming nuclear foci in response to UV, the absence of HAUSP abrogated the nuclear localization of ANXA1."
25695607
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"From a functional point of view, USP7 inhibition restores PTEN localization in CLL."
28473667
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"In contrast, USP7 reduced nuclear localization of PTEN in PC3 cells without affecting total PTEN protein levels (XREF_FIG), consistent with previously reported findings 18."
24270891