IndraLab

Statements

AR/ARv7 binds USP48. 4 / 4
| 4
reach
"To further investigate how VAV2 regulates AR/ARv7 stabilization, the interaction between AR/ARv7 and USP48 was assessed following VAV2 depletion."
40303312
reach
"Co-IP results demonstrated that VAV2 knockdown weakened the interaction between USP48 and AR/ARv7 (Fig. 8F)."
40303312
reach
"These results collectively demonstrate that VAV2 stabilizes AR/ARv7 by enhancing the association between USP48 and AR/ARv7, thereby promoting Enzalutamide resistance."
40303312
reach
"USP48 emerged as the only candidate common to both analyses, and co-IP assays confirmed interactions between USP48, VAV2, and AR/ARv7."
40303312