IndraLab

Statements

reach
"More recently, an elegant study by Bukiya et al. (2014) identified a distinct pocket as the EtOH-recognition site that is placed between the calcium-sensors and gate of the channel α subunit, supporting a direct interaction between EtOH and the BK channel."
36866357
reach
"Although the molecular interactions between ethanol and the BK channel remain largely unknown, channel activation occurs in reconstituted lipid bilayers, suggesting a direct ethanol action on the channel that does not require diffusible second messengers or accessory subunits."
26113050