IndraLab

Statements

CANX binds ABCA1 and nef. 2 / 2
| 2
sparser
"Nef disrupted interaction between calnexin and ABCA1 but increased affinity and enhanced interaction of calnexin with HIV-1 gp160."
25170080
sparser
"We studied molecular details of Nef–calnexin and Nef–ABCA1 interactions and identified a compound, which blocked Nef–calnexin interaction and partially restored ABCA1 activity in HIV-infected cells (Hunegnaw et al. xref ), modified the compound for better solubility (Adzhubei et al. xref ), and predicted a series of compounds for potential development as inhibitors of Nef-mediated co-morbidities of HIV infection by virtual screening (Adzhubei et al. xref )."
34786027