IndraLab

Statements


USP4 inhibits activity. 4 / 4
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"Furthermore, we demonstrated that USP4 inhibited p53-mediated transcriptional activity in wild-type but not HDAC2 knockdown U2OS cells in response to DNA damage or not ( xref )."

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"As a consequence, USP4 inhibited p53-mediated luciferase activity in wild-type but not HDAC2 knockdown H1299 cells that were transfected with p53 ( xref )."

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"In this screen, USP4 significantly inhibited the TAK1-induced NF-κB luciferase reporter activity whereas other USPs had no or less effects ( xref )."

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"USP4 inhibits NF-κB transcriptional activity through HDAC2."