IndraLab

Statements

USP17L2 deubiquitinates CDC25A. 3 / 4
1 | 3
reach
"Dub3 knockdown in cells increased Cdc25A ubiquitylation and degradation, resulting in reduced Cdk and Cyclin activity and arrest at G1/S and G2/M phases of the cell cycle."
20228808
reach
"DUB3 and USP17 mediates deubiquitination of CDC25A, preventing CDC25A degradation by the proteasome during the G1/S and G2/M phases promoting cell-cycle progression [XREF_BIBR]."
28031783
reach
"We also assessed the level of ubiquitin hydrolase DUB3 that is known to deubiquitylate and stabilize CDC25A 46."
29416040