IndraLab

Statements


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"Cathepsin K inhibition induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x mediated Bim protein stabilization."

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"Loss of endogenous Usp27x enhances the Bim degrading activity of oncogenic Raf."

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"USP27x DUB antagonizes the Raf-ERK Bim degradation pathway thus stabilizing Bim expression."