IndraLab

Statements

USP27X inhibits BCL2L11. 3 / 3

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"Cathepsin K inhibition induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x mediated Bim protein stabilization."

31901727

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"Loss of endogenous Usp27x enhances the Bim degrading activity of oncogenic Raf."

27013495

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"USP27x DUB antagonizes the Raf-ERK Bim degradation pathway thus stabilizing Bim expression."

29479529

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP27X inhibits BCL2L11. 3 / 3

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