IndraLab

Statements


USP8 decreases the amount of ERBB3. 2 / 2
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"Down-regulation of USP8 inhibited cell proliferation and cell metastasis and also reduced the HER-3 expression."

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"USP8 or USP9X silencing increased HER3 protein level in basal conditions (medium alone) in BxPC3 cells, suggesting that each deubiquitinase promotes basal HER3 degradation by stabilizing ITCH, as proposed for USP8 [XREF_BIBR]."