IndraLab

Statements

BAP1 deubiquitinates TUBG. 6 / 6
| 6
reach
"BAP1 can deubiquitinate γ-tubulin [32], as well as microspherule protein 1 (MCRS1), a protein that caps the minus ends of mitotic microtubules to prevent their depolymerization [33, 34]."
36550359
reach
"Another study showed de-ubiquitination of gamma-tubulin by BAP1 prevents chromosome instability in breast cancer cells [15]."
26300492
reach
"20 Additionally, loss of BAP1 or its DUB activity reduces deubiquitination of Gamma-tubulin in breast cancer cell lines, which may be attributed to the perturbation of mitotic spindle fiber formation [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
35317997
reach
"While the mechanism remains to be fully elucidated, it seems that deubiquitylation of gamma-tubulin by BAP1 during mitosis allows proper spindle organisation and function [XREF_BIBR]."
28900014
reach
"Deubiquitination of gamma-tubulin by BAP1 prevents chromosome instability in breast cancer cells."
25228651
reach
"A recent study has linked the deubiquitination of gamma-tubulin by BAP1 to breast cancer."
25605410