IndraLab

Statements

USP13 ubiquitinates TWIST1. 2 / 2
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"USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination."
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reach
"Moreover, USP13 had no effect on the ubiquitination of Twist1 by β-Trcp1, presumably due to the ineffectiveness of USP13 in Twist1 phosphorylation.As a typical transcription factor, Twist1 can recognize and bind to the E-box region of downstream gene promoters to activate or inhibit the transcription of target genes [68]."
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