IndraLab

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"Phenytoin and phenobarbital inhibit human HERG potassium channels."

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"Danielsson BR, Lansdell K, Patmore L, Tomson T. Phenytoin and phenobarbital inhibit human HERG potassium channels."

No evidence text available

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"Phenytoin has been shown to inhibit HERG channels at significantly higher concentrations (IC 50 for HERG> 300muM, vs. IC 50 for VGSC ~ 10muM) [XREF_BIBR, XREF_BIBR]."