IndraLab

Statements


PF inhibits RELA. 2 / 2
| 2

reach
"Our results showed that PF could inhibit activation of NF-kappaBp65, whereas NF-kappaBp65 may contribute to inflammatory related complex cellular pathways, and it is also one of the mechanisms of its therapeutic effect on RA (XREF_FIG)."

reach
"Taken together, our study reveals a mechanism underlying TNF-alpha-induced cell apoptosis : PF could inhibit the activity of NF-kappaBp65 and apoptosis of L929 cells induced by TNF-alpha, suggesting that PF may play a role in the treatment of RA through the antagonism of TNF-alpha pathway."