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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 increases the amount of glutathione. 2 / 2

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"The UCHL1 mediated reprogramming elevated intracellular GSH levels, and consequently induced a radioresistant phenotype in a HIF-1-dependent manner."

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"The UCHL1 dependent increase in the intracellular GSH levels was significantly suppressed by silencing the expression of a key molecule of the pentose phosphate pathway, the glucose-6-phosphate dehydrogenase X linked (G6pdx) gene XREF_BIBR, XREF_BIBR."

28761052

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...