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"On the other hand, in vitro electrophysiological studies have shown that some anesthetics including halothane and pentobarbital can significantly suppress the HERG channels ( Bachmann et al., 2002; Li[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Pentobarbital induced HERG inhibition was not dependent on voltage but influenced the deactivation kinetics and shifted half-maximal activation to more negative voltages."