IndraLab

Statements

RvD1 inhibits MAP3K7. 4 / 4
| 4
reach
"We further illustrate that RvD1 inhibits TAK1 activation, at least partly, via perturbing the association of a poly (I : C) and mediated complex involving TAK1, TAB1 and TRAF6."
25320283
reach
"Given that the RvD1 inhibits TAK1 activation and activates-arrestin, it is very likely that RvD1 also interferes with the complex formation via a similar mechanism."
25320283
reach
"Given that the specific inhibition of TAK1 blocks pro inflammatory signaling and that RvD1 attenuates TAK1 activation, we hypothesized that RvD1 inhibits TAK1 activation by interfering with the formation of poly (I : C)-mediated signaling components."
25320283
reach
"It is worthwhile to note that docosahexaenoic acid (DHA), a precursor of RvD1, was shown to inhibit TAK1 activation via a GPR120 dependent signaling pathway."
25320283